most citedOptimizing Drug Design by Merging Generative AI With Active Learning Frameworks

9 citations · 9 across the 1 of their papers we have counts for

collaborators

5 papers

q-bio.QM2024

Character-level Tokenizations as Powerful Inductive Biases for RNA Foundational Models

Adrián Morales-Pastor, Raquel Vázquez-Reza, Miłosz Wieczór +5

RNA is a vital biomolecule with numerous roles and functions within cells, and interest in targeting it for therapeutic purposes has grown significantly in recent years. However, f…

q-bio.BM20244 cited

Are Protein Language Models Compute Optimal?

Yaiza Serrano, Álvaro Ciudad, Alexis Molina

While protein language models (pLMs) have transformed biological research, the scaling laws governing their improvement remain underexplored. By adapting methodologies from NLP sca…

cs.LG20241 cited

Scoreformer: A Surrogate Model For Large-Scale Prediction of Docking Scores

Álvaro Ciudad, Adrián Morales-Pastor, Laura Malo +3

In this study, we present ScoreFormer, a novel graph transformer model designed to accurately predict molecular docking scores, thereby optimizing high-throughput virtual screening…

q-bio.BM2024

GeoDirDock: Guiding Docking Along Geodesic Paths

Raúl Miñán, Javier Gallardo, Álvaro Ciudad +1

This work introduces GeoDirDock (GDD), a novel approach to molecular docking that enhances the accuracy and physical plausibility of ligand docking predictions. GDD guides the deno…

q-bio.BM20239 cited

Optimizing Drug Design by Merging Generative AI With Active Learning Frameworks

Isaac Filella-Merce, Alexis Molina, Marek Orzechowski +7

Traditional drug discovery programs are being transformed by the advent of machine learning methods. Among these, Generative AI methods (GM) have gained attention due to their abil…