234 citations · 471 across the 5 of their papers we have counts for
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Physical Properties of Biological Membranes
Thomas Heimburg
Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that ca…
The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics
Andreas Blicher, Katarzyna Wodzinska, Matthias Fidorra +2
We investigate the permeability of lipid membranes for fluorescence dyes and ions. We find that permeability reaches a maximum close to the chain melting transition of the membrane…
Melting of Single Lipid Components in Binary Lipid Mixtures: A Comparison between FTIR Spectroscopy, DSC and Monte Carlo Simulations
M. Fidorra, T. Heimburg, H. M. Seeger
Monte Carlo (MC) Simulations, Differential Scanning Calorimetry (DSC) and Fourier Transform InfraRed (FTIR) spectroscopy were used to study the melting behavior of single lipid com…
The thermodynamics of general anesthesia
Thomas Heimburg, Andrew D. Jackson
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly rel…
Defect formation of lytic peptides in lipid membranes and their influence on the thermodynamic properties of the pore environment
Vitaliy Oliynyk, Udo Kaatze, Thomas Heimburg
We present an experimental study of the pore formation processes of small amphipathic peptides in model phosphocholine lipid membranes. We used atomic force microscopy to character…