2 papers
physics.bio-ph2023
The one-message-per-cell-cycle rule: A conserved minimum transcription level for essential genes
Teresa W. Lo, Han Kyou James Choi, Dean Huang +1
The inherent stochasticity of cellular processes leads to significant cell-to-cell variation in protein abundance. Although this noise has already been characterized and modeled, i…
physics.bio-ph2022
The high-resolution in vivo measurement of replication fork velocity and pausing by lag-time analysis
Dean Huang, Anna E. Johnson, Brandon S. Sim +3
An important step towards understanding the mechanistic basis of the central dogma is the quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in th…