88 citations · 118 across the 3 of their papers we have counts for
3 papers
The use of external controls: To what extent can it currently be recommended?
Hans Ulrich Burger, Christoph Gerlinger, Chris Harbron +4
With more and better clinical data being captured outside of clinical studies and greater data sharing of clinical studies, external controls may become a more attractive alternati…
A Comparison of Estimand and Estimation Strategies for Clinical Trials in Early Parkinson's Disease
Alessandro Noci, Marcel Wolbers, Markus Abt +4
Parkinson's disease (PD) is a chronic, degenerative neurological disorder. PD cannot be prevented, slowed or cured as of today but highly effective symptomatic treatments are avail…
A multistate model for early decision making in oncology
Ulrich Beyer, David Dejardin, Matthias Meller +2
The development of oncology drugs progresses through multiple phases, where after each phase a decision is made about whether to move a molecule forward. Early phase efficacy decis…