32 citations · 33 across the 2 of their papers we have counts for
5 papers
A survey of open questions in adaptive therapy: bridging mathematics and clinical translation
Jeffrey West, Fred Adler, Jill Gallaher +9
Adaptive therapy is a dynamic cancer treatment protocol that updates (or "adapts") treatment decisions in anticipation of evolving tumor dynamics. This broad term encompasses many…
Working With Convex Responses: Antifragility From Finance to Oncology
Nassim Nicholas Taleb, Jeffrey West
We extend techniques and learnings about the stochastic properties of nonlinear responses from finance to medicine, particularly oncology where it can inform dosing and interventio…
Universal principles of cell population growth follow from local contact inhibition
Gregory J. Kimmel, Sadegh Marzban, Mehdi Damaghi +4
Cancer cell populations often exhibit remarkably similar growth laws despite their heterogeneity. Explanations of universal cell population growth remain partly unresolved to this…
The Prisoner's dilemma as a cancer model
Jeffrey West, Zaki Hasnain, Jeremy Mason +1
Tumor development is an evolutionary process in which a heterogeneous population of cells with differential growth capabilities compete for resources in order to gain a proliferati…
An evolutionary model of tumor cell kinetics and the emergence of molecular heterogeneity driving Gompertzian growth
Jeffrey West, Zaki Hasnain, Paul Macklin +1
A cell-molecular based evolutionary model of tumor development driven by a stochastic Moran birth-death process is developed, where each cell carries molecular information represen…