3 papers
stat.ME2025
Manifold-Constrained Gaussian Processes for Inference of Mixed-effects Ordinary Differential Equations with Application to Pharmacokinetics
Yuxuan Zhao, Samuel W. K. Wong
Pharmacokinetic modeling using ordinary differential equations (ODEs) has an important role in dose optimization studies, where dosing must balance sustained therapeutic efficacy w…
stat.ME2024
Inference for Delay Differential Equations Using Manifold-Constrained Gaussian Processes
Yuxuan Zhao, Samuel W. K. Wong
Dynamic systems described by differential equations often involve feedback among system components. When there are time delays for components to sense and respond to feedback, dela…
q-bio.PE2022
A Comparative Study of Compartmental Models for COVID-19 Transmission in Ontario, Canada
Yuxuan Zhao, Samuel W. K. Wong
The number of confirmed COVID-19 cases reached over 1.3 million in Ontario, Canada by June 4, 2022. The continued spread of the virus underlying COVID-19 has been spurred by the em…