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math.ST2022
Bias of the additive hazard model in the presence of causal effect heterogeneity
Richard Post, Edwin van den Heuvel, Hein Putter
Hazard ratios are prone to selection bias, compromising their use as causal estimands. On the other hand, the hazard difference has been shown to remain unaffected by the selection…
math.ST2022
The built-in selection bias of hazard ratios formalized
Richard Post, Edwin van den Heuvel, Hein Putter
It is known that the hazard ratio lacks a useful causal interpretation. Even for data from a randomized controlled trial, the hazard ratio suffers from built-in selection bias as,…