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ADNP-15: An Open-Source Histopathological Dataset for Neuritic Plaque Segmentation in Human Brain Whole Slide Images with Frequency Domain Image Enhancement for Stain Normalization
Chenxi Zhao, Jianqiang Li, Qing Zhao +7
Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by amyloid-beta plaques and tau neurofibrillary tangles, which serve as key histopathological features. The i…
Graph Theory and GNNs to Unravel the Topographical Organization of Brain Lesions in Variants of Alzheimer's Disease Progression
Gabriel Jimenez, Leopold Hebert-Stevens, Benoit Delatour +2
In this study, we proposed and evaluated a graph-based framework to assess variations in Alzheimer's disease (AD) neuropathologies, focusing on classic (cAD) and rapid (rpAD) progr…
Frequency Disentangled Learning for Segmentation of Midbrain Structures from Quantitative Susceptibility Mapping Data
Guanghui Fu, Gabriel Jimenez, Sophie Loizillon +8
One often lacks sufficient annotated samples for training deep segmentation models. This is in particular the case for less common imaging modalities such as Quantitative Susceptib…
Visual deep learning-based explanation for neuritic plaques segmentation in Alzheimer's Disease using weakly annotated whole slide histopathological images
Gabriel Jimenez, Anuradha Kar, Mehdi Ounissi +5
Quantifying the distribution and morphology of tau protein structures in brain tissues is key to diagnosing Alzheimer's Disease (AD) and its subtypes. Recently, deep learning (DL)…
Computational Pathology for Brain Disorders
Gabriel Jimenez, Daniel Racoceanu
Non-invasive brain imaging techniques allow understanding the behavior and macro changes in the brain to determine the progress of a disease. However, computational pathology provi…
Fourier Disentangled Multimodal Prior Knowledge Fusion for Red Nucleus Segmentation in Brain MRI
Guanghui Fu, Gabriel Jimenez, Sophie Loizillon +9
Early and accurate diagnosis of parkinsonian syndromes is critical to provide appropriate care to patients and for inclusion in therapeutic trials. The red nucleus is a structure o…