20 citations · 36 across the 2 of their papers we have counts for
2 papers
q-bio.QM2022★ 16 cited
De novo PROTAC design using graph-based deep generative models
Divya Nori, Connor W. Coley, Rocío Mercado
PROteolysis TArgeting Chimeras (PROTACs) are an emerging therapeutic modality for degrading a protein of interest (POI) by marking it for degradation by the proteasome. Recent deve…
cs.LG2021★ 20 cited
Amortized Tree Generation for Bottom-up Synthesis Planning and Synthesizable Molecular Design
Wenhao Gao, Rocío Mercado, Connor W. Coley
Molecular design and synthesis planning are two critical steps in the process of molecular discovery that we propose to formulate as a single shared task of conditional synthetic p…