activity
20222025
most citedLabel-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography

42 citations · 99 across the 9 of their papers we have counts for

collaborators

9 papers

physics.med-ph2025★ 8 cited

Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise

Yuanke Feng, Shumpei Fujimura, Yiheng Lim +6

Dynamic optical coherence tomography (DOCT) enables label-free functional imaging by capturing temporal OCT signal variations caused by intracellular and intratissue motions. Howev…

physics.optics2025★ 1 cited

In vivo dynamic optical coherence tomography of human skin with hardware- and software-based motion correction

Yu Guo, Rion Morishita, Ibrahim Abd El-Sadek +10

In vivo application of dynamic optical coherence tomography (DOCT) is hindered by bulk motion of the sample. We demonstrate DOCT imaging of \invivo human skin by adopting a sample-…

physics.optics2024★ 10 cited

Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers

Rion Morishita, Pradipta Mukherjee, Ibrahim Abd El-Sadek +8

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratiss…

physics.bio-ph2024★ 7 cited

Optical-coherence-tomography-based deep-learning scatterer-density estimator using physically accurate noise model

Thitiya Seesan, Pradipta Mukherjee, Ibrahim Abd El-Sadek +4

We demonstrate a deep-learning-based scatterer density estimator (SDE) that processes local speckle patterns of optical coherence tomography (OCT) images and estimates the scattere…

physics.optics2023★ 8 cited

Polarization-artifact reduction and accuracy improvement of Jones-matrix polarization-sensitive optical coherence tomography by multi-focus averaging

Lida Zhu, Shuichi Makita, Junya Tamaoki +4

Polarization-sensitive optical coherence tomography (PS-OCT) is a promising biomedical imaging tool for differentiation of various tissue properties. However, the presence of multi…

physics.optics2023★ 19 cited

Theoretical model for en face optical coherence tomography imaging and its application to volumetric differential contrast imaging

Kiriko Tomita, Shuichi Makita, Naoki Fukutake +10

A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are pres…

physics.bio-ph2023★ 42 cited

Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography

Rion Morishita, Pradipta Mukherjee, Ibrahim Abd El-Sadek +8

An organoid is a three-dimensional (3D) in vitro cell culture emulating human organs. We applied 3D dynamic optical coherence tomography (DOCT) to visualize the intratissue and int…

physics.med-ph2022★ 2 cited

Label-free drug response evaluation of human derived tumor spheroids using three-dimensional dynamic optical coherence tomography

Ibrahim Abd El-Sadek, Larina Tzu-Wei Shen, Tomoko Mori +5

We demonstrate label-free drug response evaluations of human breast (MCF-7) and colon (HT-29) cancer spheroids via dynamic optical coherence tomography (OCT). The MCF-7 and HT-29 s…

physics.med-ph2022★ 2 cited

Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography

Pradipta Mukherjee, Shinichi Fukuda, Donny Lukmanto +10

Label-free metabolic imaging of non-alcoholic fatty liver disease (NAFLD) mouse liver is demonstrated ex vivo by dynamic optical coherence tomography (OCT). The NAFLD mouse is a me…