activity
20222026
most citedCurrent and future directions in network biology

108 citations · 120 across the 16 of their papers we have counts for

collaborators

16 papers

cs.CV2026

TopoAgent: An Agentic Framework for Automated Topology Learning in Medical Imaging

Guangyu Meng, Pengfei Gu, Xueyang Li +3

Topological data analysis (TDA), particularly persistent homology (PH), captures geometric structural properties in medical images (e.g., connected components, loops, shape charact…

cs.CV2026

TopoCL: Topological Contrastive Learning for Medical Imaging

Guangyu Meng, Pengfei Gu, Peixian Liang +3

Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance f…

cs.CV2025

TopoImages: Incorporating Local Topology Encoding into Deep Learning Models for Medical Image Classification

Pengfei Gu, Hongxiao Wang, Yejia Zhang +3

Topological structures in image data, such as connected components and loops, play a crucial role in understanding image content (e.g., biomedical objects). % Despite remarkable su…

cs.CV2025

Hierarchical LoG Bayesian Neural Network for Enhanced Aorta Segmentation

Delin An, Pan Du, Pengfei Gu +2

Accurate segmentation of the aorta and its associated arch branches is crucial for diagnosing aortic diseases. While deep learning techniques have significantly improved aorta segm…

cs.CV2024

Sli2Vol+: Segmenting 3D Medical Images Based on an Object Estimation Guided Correspondence Flow Network

Delin An, Pengfei Gu, Milan Sonka +2

Deep learning (DL) methods have shown remarkable successes in medical image segmentation, often using large amounts of annotated data for model training. However, acquiring a large…

cs.CV2024

FCNR: Fast Compressive Neural Representation of Visualization Images

Yunfei Lu, Pengfei Gu, Chaoli Wang

We present FCNR, a fast compressive neural representation for tens of thousands of visualization images under varying viewpoints and timesteps. The existing NeRVI solution, albeit…

cs.CV2024

Boosting Medical Image Classification with Segmentation Foundation Model

Pengfei Gu, Zihan Zhao, Hongxiao Wang +5

The Segment Anything Model (SAM) exhibits impressive capabilities in zero-shot segmentation for natural images. Recently, SAM has gained a great deal of attention for its applicati…

cs.CV2024

Self Pre-training with Topology- and Spatiality-aware Masked Autoencoders for 3D Medical Image Segmentation

Pengfei Gu, Huimin Li, Yejia Zhang +2

Masked Autoencoders (MAEs) have been shown to be effective in pre-training Vision Transformers (ViTs) for natural and medical image analysis problems. By reconstructing missing pix…

cs.CV2024

Path-GPTOmic: A Balanced Multi-modal Learning Framework for Survival Outcome Prediction

Hongxiao Wang, Yang Yang, Zhuo Zhao +3

For predicting cancer survival outcomes, standard approaches in clinical research are often based on two main modalities: pathology images for observing cell morphology features, a…

q-bio.MN2023★ 108 cited

Current and future directions in network biology

Marinka Zitnik, Michelle M. Li, Aydin Wells +34

Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseas…

cs.CV2023★ 6 cited

SamDSK: Combining Segment Anything Model with Domain-Specific Knowledge for Semi-Supervised Learning in Medical Image Segmentation

Yizhe Zhang, Tao Zhou, Shuo Wang +3

The Segment Anything Model (SAM) exhibits a capability to segment a wide array of objects in natural images, serving as a versatile perceptual tool for various downstream image seg…

cs.CV2023

SwIPE: Efficient and Robust Medical Image Segmentation with Implicit Patch Embeddings

Yejia Zhang, Pengfei Gu, Nishchal Sapkota +1

Modern medical image segmentation methods primarily use discrete representations in the form of rasterized masks to learn features and generate predictions. Although effective, thi…

cs.LG2023★ 2 cited

Graph-Free Learning in Graph-Structured Data: A More Efficient and Accurate Spatiotemporal Learning Perspective

Xu Wang, Pengfei Gu, Pengkun Wang +4

Spatiotemporal learning, which aims at extracting spatiotemporal correlations from the collected spatiotemporal data, is a research hotspot in recent years. And considering the inh…

cs.CV2022

Keep Your Friends Close & Enemies Farther: Debiasing Contrastive Learning with Spatial Priors in 3D Radiology Images

Yejia Zhang, Nishchal Sapkota, Pengfei Gu +3

Understanding of spatial attributes is central to effective 3D radiology image analysis where crop-based learning is the de facto standard. Given an image patch, its core spatial p…

cs.CV2022★ 4 cited

ConvFormer: Combining CNN and Transformer for Medical Image Segmentation

Pengfei Gu, Yejia Zhang, Chaoli Wang +1

Convolutional neural network (CNN) based methods have achieved great successes in medical image segmentation, but their capability to learn global representations is still limited…

cs.CV2022

A Point in the Right Direction: Vector Prediction for Spatially-aware Self-supervised Volumetric Representation Learning

Yejia Zhang, Pengfei Gu, Nishchal Sapkota +3

High annotation costs and limited labels for dense 3D medical imaging tasks have recently motivated an assortment of 3D self-supervised pretraining methods that improve transfer le…