2 papers
cs.LG2022
Protein language model rescue mutations highlight variant effects and structure in clinically relevant genes
Onuralp Soylemez, Pablo Cordero
Despite being self-supervised, protein language models have shown remarkable performance in fundamental biological tasks such as predicting impact of genetic variation on protein s…
cs.LG2022
Bayesian tensor factorization for predicting clinical outcomes using integrated human genetics evidence
Onuralp Soylemez
The approval success rate of drug candidates is very low with the majority of failure due to safety and efficacy. Increasingly available high dimensional information on targets, dr…