2 papers
q-bio.GN2010
Shape-based peak identification for ChIP-Seq
Valerie Hower, Steven N. Evans, Lior Pachter
We present a new algorithm for the identification of bound regions from ChIP-seq experiments. Our method for identifying statistically significant peaks from read coverage is inspi…
q-bio.GN2010
Coverage statistics for sequence census methods
Steven N. Evans, Valerie Hower, Lior Pachter
Background: We study the statistical properties of fragment coverage in genome sequencing experiments. In an extension of the classic Lander-Waterman model, we consider the effect…