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stat.ME2024
Multivariate group sequential tests for global summary statistics
Abigail J. Burdon, Thomas Jaki
We describe group sequential tests which efficiently incorporate information from multiple endpoints allowing for early stopping at pre-planned interim analyses. We formulate a tes…
stat.ME2022★ 2 cited
Joint modelling of longitudinal and time-to-event data applied to group sequential clinical trials
Abigail J. Burdon, Lisa V. Hampson, Christopher Jennison
Often in Phase 3 clinical trials measuring a long-term time-to-event endpoint, such as overall survival or progression-free survival, investigators also collect repeated measures o…