activity
20222026
most citedThe effects of leaflet material properties on the simulated function of regurgitant mitral valves

11 citations · 14 across the 7 of their papers we have counts for

collaborators

9 papers

cs.CE2026

FUSE: A Partitioned Field-Exchange Framework for Coupling Physics Simulations in FEBio

Steve A. Maas, Farhan Muhib, Jeffrey A. Weiss

Computational biomechanics increasingly requires models that combine mechanics, transport, chemistry, and biological regulation across different spatial and temporal scales. The FE…

q-bio.QM2026★ 1 cited

An open-source computational framework for immersed fluid-structure interaction modeling using FEBio and MFEM

Ryan T. Black, Steve A. Maas, Wensi Wu +4

Fluid-structure interaction (FSI) simulation of biological systems presents significant computational challenges, particularly for applications involving large structural deformati…

physics.med-ph2026

Effect of Right Ventricular Outflow Tract Material Properties on Simulated Transcatheter Pulmonary Placement

Jalaj Maheshwari, Wensi Wu, Christopher N. Zelonis +9

FE simulations emulating TPV system deployment in patient-specific right ventricular outflow tracts (RVOT) assume material properties for the RVOT and adjacent tissues. Sensitivity…

physics.med-ph2025

Simulation of Transcatheter Therapies for Atrioventricular Valve Regurgitation in an Open-Source Finite Element Simulation Framework

Seda Aslan, Nicolas R. Mangine, Devin W. Laurence +8

Purpose: Transcatheter edge-to-edge repair (TEER) and annuloplasty devices are increasingly used to treat mitral valve regurgitation, yet their mechanical effects and interactions…

q-bio.TO2025

Integrated Open-Source Framework for Simulation of Transcatheter Pulmonary Valves in Native Right Ventricular Outflow Tracts

Christopher N. Zelonis, Jalaj Maheshwari, Wensi Wu +14

Pulmonary insufficiency is a consequence of transannular patch repair in Tetralogy of Fallot (ToF), leading to late morbidity and mortality. Transcatheter native outflow tract pulm…

physics.med-ph2024

Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure

Nicolas R. Mangine, Devin W. Laurence, Patricia M. Sabin +9

Many approaches have been used to model chordae tendineae geometries in finite element simulations of atrioventricular heart valves. Unfortunately, current "functional" chordae ten…

physics.med-ph2024★ 2 cited

FEBio FINESSE: An open-source finite element simulation approach to estimate in vivo heart valve strains using shape enforcement

Devin W. Laurence, Patricia M. Sabin, Analise M. Sulentic +4

Finite element simulations are an enticing tool to evaluate heart valve function in healthy and diseased patients; however, patient-specific simulations derived from 3D echocardiog…

physics.med-ph2023★ 11 cited

The effects of leaflet material properties on the simulated function of regurgitant mitral valves

Wensi Wu, Stephen Ching, Patricia Sabin +5

Advances in three-dimensional imaging provide the ability to construct and analyze finite element (FE) models to evaluate the biomechanical behavior and function of atrioventricula…

q-bio.TO2022

A Computational Framework for Atrioventricular Valve Modeling using Open-Source Software

Wensi Wu, Stephen Ching, Steve A. Maas +4

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational m…