2 papers
stat.AP2023
Mixture of regressions with multivariate responses for discovering subtypes in Alzheimer's biomarkers with detection limits
Ganzhong Tian, John Hanfelt, James Lah +1
There is no gold standard for the diagnosis of Alzheimer's disease (AD), except from autopsies. Unsupervised learning can provide insight into the pathophysiology of AD. A mixture…
stat.ME2022
Latent Class Analysis with Semi-parametric Proportional Hazards Submodel for Time-to-event Data
Teng Fei, John Hanfelt, Limin Peng
Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maxim…