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cs.AI2026
ProtLingo: Efficient Protein Language Modeling via Conditional Memory and Expert Routing
Mingrui Li, Sixian Shen, Minzhang Li +4
Proteins perform diverse cellular functions, and even single amino-acid substitutions can alter stability, activity, or molecular interactions. Protein language models (PLMs) provi…
cs.AI2026
CryoACE: An Atom-centric Framework for Accurate and Automated Model Building in Cryo-EM
Minzhang Li, Mingrui Li, Weichen Qin +5
Protein automodeling from cryo-EM density maps faces unique challenges in enforcing physicochemical validity and managing conformational heterogeneity. Current solvers are often li…