2 papers
stat.ME2025
Modeling and prediction of mutation fitness on protein functionality with structural information using high-dimensional Potts model
Bingying Dai, Yinan Lin, Kejue Jia +2
Quantifying the effects of amino acid mutations in proteins presents a significant challenge due to the vast combinations of residue sites and amino acid types, making experimental…
stat.ME2022
Modeling High-Dimensional Data with Unknown Cut Points: A Fusion Penalized Logistic Threshold Regression
Yinan Lin, Wen Zhou, Zhi Geng +2
In traditional logistic regression models, the link function is often assumed to be linear and continuous in predictors. Here, we consider a threshold model that all continuous fea…