6 papers
Connectomics Informed by Large Language Models
Elinor Thompson, Tiantian He, Anna Schroder +5
Tractography is a unique method for mapping white matter connections in the brain, but tractography algorithms suffer from an inherent trade-off between sensitivity and specificity…
GenTract: Generative Global Tractography
Alec Sargood, Lemuel Puglisi, Elinor Thompson +2
Tractography is the process of inferring the trajectories of white-matter pathways in the brain from diffusion magnetic resonance imaging (dMRI). Local tractography methods, which…
CoCoLIT: ControlNet-Conditioned Latent Image Translation for MRI to Amyloid PET Synthesis
Alec Sargood, Lemuel Puglisi, James H. Cole +3
Synthesizing amyloid PET scans from the more widely available and accessible structural MRI modality offers a promising, cost-effective approach for large-scale Alzheimer's Disease…
Benchmarking GANs, Diffusion Models, and Flow Matching for T1w-to-T2w MRI Translation
Andrea Moschetto, Lemuel Puglisi, Alec Sargood +4
Magnetic Resonance Imaging (MRI) enables the acquisition of multiple image contrasts, such as T1-weighted (T1w) and T2-weighted (T2w) scans, each offering distinct diagnostic insig…
Fixed and Distributed Gene Expression Time Delays in Reaction-Diffusion Systems
Alec Sargood, Eamonn A. Gaffney, Andrew L. Krause
Time delays, modelling the process of intracellular gene expression, have been shown to have important impacts on the dynamics of pattern formation in reaction-diffusion systems. I…
Gene Expression Time Delays in Reaction-Diffusion Systems
Alec Sargood
Gene expression time delays, modelling the complex biological processes of gene transcription and translation, have been shown to play an important role in cellular dynamics. Time…