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physics.bio-ph2026

Dynamical noisy canalization in morphogenesis: lessons from Hydra regeneration

Oded Agam, Erez Braun

Developmental robustness is framed as progress through a fixed Waddington-type landscape. We argue that in morphogenesis this landscape evolves through coupled bio-signaling, mecha…

physics.bio-ph2026

Rupture-Repair Cycles in Regenerating Hydra Tissues

Oded Agam, Erez Braun

Destructive mechanical breakdowns and fractures are ubiquitous events in driven physical matter; living tissues, by contrast, can rupture repeatedly while restoring integrity. Here…

physics.bio-ph2025

The Dual Nature of Body-Axis Formation in Hydra Regeneration: Polarity-Morphology Concurrency

Oded Agam, Erez Braun

The formation of a body-axis is central to animal development and involves both polarity and morphology. While polarity is traditionally associated with biochemical patterning, the…

physics.bio-ph2025

Pattern formation in e. coli through negative chemotaxis: instability, condensation, and merging

Nir Livne, Ady Vaknin, Oded Agam

Motile bacteria can migrate along chemical gradients in a process known as chemotaxis. When exposed to uniform environmental stress, Escherichia coli cells coordinate their chemota…

physics.bio-ph2024

Fluctuation-Driven Morphological Patterning: A Novel Approach to Morphogenesis

Oded Agam, Erez Braun

Recent experimental investigations into Hydra regeneration revealed a remarkable phenomenon: the morphological transformation of a tissue fragment from the incipient spherical conf…