most citedCombining the target trial and estimand frameworks to define the causal estimand: an application using real-world data to contextualize a single-arm trial

3 citations · 3 across the 1 of their papers we have counts for

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stat.AP2022★ 3 cited

Combining the target trial and estimand frameworks to define the causal estimand: an application using real-world data to contextualize a single-arm trial

Lisa V Hampson, Jufen Chu, Aiesha Zia +5

Single-arm trials (SATs) may be used to support regulatory submissions in settings where there is a high unmet medical need and highly promising early efficacy data undermine the e…