2 citations · 3 across the 3 of their papers we have counts for
3 papers
Estimation of treatment policy estimands for continuous outcomes using off treatment sequential multiple imputation
Thomas Drury, Juan J Abellan, Nicky Best +1
The estimands framework outlined in ICH E9 (R1) describes the components needed to precisely define the effects to be estimated in clinical trials, which includes how post-baseline…
Implementation and pratical aspects of quantitative decision-making in clinical drug development
Juan J. Abellan, Nicolas Bonnet, Alex Carlton +7
Quantitative decision-making (QDM) principles address the issues related to the mapping of results to decisions, the synthesis of information and the quantification of uncertainty.…
Awareness and use of quantitative decision-making methods in pharmaceutical development
Guido Thömmes, Martin Oliver Sailer, Nicolas Bonnet +3
The pharmaceutical industry has experienced increasing costs and sustained high attrition rates in drug development over the last years. One proposal that addresses this challenge…