activity
20222026
most citedMarker and source-marker reprogramming of Most Permissive Boolean networks and ensembles with BoNesis

10 citations · 12 across the 6 of their papers we have counts for

collaborators

6 papers

math.OC2026

A Bilevel Integer Programming Approach for the Synchronous Attractor Control Problem

Kyungduk Moon, Kangbok Lee, Loïc Paulevé

Boolean networks are dynamical models of disease development in which the activation levels of genes are represented by binary variables. Given a Boolean network, controls represen…

q-bio.MN2026

Prediction of source nutrients for microorganisms using metabolic networks

Olivia Bulka, Chabname Ghassemi Nedjad, Loïc Paulevé +2

Metagenomics has lowered the barrier to microbial discovery--enabling the identification of novel microbes without isolation--but cultures remain imperative for the deep study of m…

cs.DM2024

Phenotype control and elimination of variables in Boolean networks

Elisa Tonello, Loïc Paulevé

We investigate how elimination of variables can affect the asymptotic dynamics and phenotype control of Boolean networks. In particular, we look at the impact on minimal trap space…

cs.DM2023★ 2 cited

Attractor identification in asynchronous Boolean dynamics with network reduction

Elisa Tonello, Loïc Paulevé

Identification of attractors, that is, stable states and sustained oscillations, is an important step in the analysis of Boolean models and exploration of potential variants. We de…

eess.SY2022★ 10 cited

Marker and source-marker reprogramming of Most Permissive Boolean networks and ensembles with BoNesis

Loïc Paulevé

Boolean networks (BNs) are discrete dynamical systems with applications to the modeling of cellular behaviors. In this paper, we demonstrate how the software BoNesis can be employe…

q-bio.QM2022

BioSimulators: a central registry of simulation engines and services for recommending specific tools

Bilal Shaikh, Lucian P. Smith, Dan Vasilescu +68

Computational models have great potential to accelerate bioscience, bioengineering, and medicine. However, it remains challenging to reproduce and reuse simulations, in part, becau…