3 papers
q-bio.PE2022
A model for malaria treatment evaluation in the presence of multiple species
Camelia R. Walker, Roslyn I. Hickson, Edmond Chang +8
Plasmodium (P.) falciparum and P. vivax are the two most common causes of malaria. While the majority of deaths and severe morbidity are due to P. falciparum, P. vivax poses a grea…
stat.ME2022
Making SMART decisions in prophylaxis and treatment studies
Robert K. Mahar, Katherine J. Lee, Bibhas Chakraborty +2
The optimal prophylaxis, and treatment if the prophylaxis fails, for a disease may be best evaluated using a sequential multiple assignment randomised trial (SMART). A SMART is a m…
stat.ME2021
Handling missing data when estimating causal effects with Targeted Maximum Likelihood Estimation
S. Ghazaleh Dashti, Katherine J. Lee, Julie A. Simpson +3
Targeted Maximum Likelihood Estimation (TMLE) is increasingly used for doubly robust causal inference, but how missing data should be handled when using TMLE with data-adaptive app…