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q-bio.QM2022★ 1 cited
Predicting Survival of Tongue Cancer Patients by Machine Learning Models
Angelos Vasilopoulos, Nan Miles Xi
Tongue cancer is a common oral cavity malignancy that originates in the mouth and throat. Much effort has been invested in improving its diagnosis, treatment, and management. Surgi…
q-bio.QM2022
Tuning hyperparameters of doublet-detection methods for single-cell RNA sequencing data
Nan Miles Xi, Angelos Vasilopoulos
The existence of doublets in single-cell RNA sequencing (scRNA-seq) data poses a great challenge in downstream data analysis. Computational doublet-detection methods have been deve…
q-bio.QM2022
Prediction of Drug-Induced TdP Risks Using Machine Learning and Rabbit Ventricular Wedge Assay
Nan Miles Xi, Dalong Patrick Huang
The evaluation of drug-induced Torsades de pointes (TdP) risks is crucial in drug safety assessment. In this study, we discuss machine learning approaches in the prediction of drug…