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20222024
most citedRawHash: Enabling Fast and Accurate Real-Time Analysis of Raw Nanopore Signals for Large Genomes

46 citations · 139 across the 15 of their papers we have counts for

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6 papers · 1 filter

q-bio.GN2024

Rawsamble: Overlapping and Assembling Raw Nanopore Signals using a Hash-based Seeding Mechanism

Can Firtina, Maximilian Mordig, Harun Mustafa +7

Raw nanopore signal analysis is a common approach in genomics to provide fast and resource-efficient analysis without translating the signals to bases (i.e., without basecalling).…

q-bio.GN2023

MetaTrinity: Enabling Fast Metagenomic Classification via Seed Counting and Edit Distance Approximation

Arvid E. Gollwitzer, Mohammed Alser, Joel Bergtholdt +5

Metagenomics, the study of genome sequences of diverse organisms cohabiting in a shared environment, has experienced significant advancements across various medical and biological…

q-bio.GN2023★ 2 cited

RawAlign: Accurate, Fast, and Scalable Raw Nanopore Signal Mapping via Combining Seeding and Alignment

Joël Lindegger, Can Firtina, Nika Mansouri Ghiasi +3

Nanopore sequencers generate raw electrical signals representing the contents of a biological sequence molecule passing through the nanopore. These signals can be analyzed directly…

q-bio.GN2023★ 19 cited

RawHash2: Mapping Raw Nanopore Signals Using Hash-Based Seeding and Adaptive Quantization

Can Firtina, Melina Soysal, Joël Lindegger +1

Summary: Raw nanopore signals can be analyzed while they are being generated, a process known as real-time analysis. Real-time analysis of raw signals is essential to utilize the u…

q-bio.GN2023★ 46 cited

RawHash: Enabling Fast and Accurate Real-Time Analysis of Raw Nanopore Signals for Large Genomes

Can Firtina, Nika Mansouri Ghiasi, Joel Lindegger +4

Nanopore sequencers generate electrical raw signals in real-time while sequencing long genomic strands. These raw signals can be analyzed as they are generated, providing an opport…

q-bio.GN2022★ 12 cited

TargetCall: Eliminating the Wasted Computation in Basecalling via Pre-Basecalling Filtering

Meryem Banu Cavlak, Gagandeep Singh, Mohammed Alser +6

Basecalling is an essential step in nanopore sequencing analysis where the raw signals of nanopore sequencers are converted into nucleotide sequences, i.e., reads. State-of-the-art…