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20222026
most citedModeling principles for a physiology-based whole-body model of human metabolism

1 citations · 1 across the 6 of their papers we have counts for

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q-bio.QM2026

Multi-scale Metabolic Modeling and Simulation

Peter E. Carstensen, Teddy Groves, Lars K. Nielsen +3

Biological systems are governed by coupled interactions between intracellular metabolism and bioreactor operation that span multiple time scales. Constraint-based metabolic models…

q-bio.QM2024★ 1 cited

Modeling principles for a physiology-based whole-body model of human metabolism

Laura Hjort Blicher, Peter Emil Carstensen, Jacob Bendsen +4

Physiological whole-body models are valuable tools for the development of novel drugs where understanding the system aspects is important. This paper presents a generalized model t…

q-bio.QM2024

A whole-body mathematical model of cholesterol metabolism and transport

Peter Emil Carstensen, Jacob Bendsen, Laura Hjort Blicher +2

Cardiovascular diseases are the leading cause of death. Increased levels of plasma cholesterol are consistently associated with an increased risk of cardiovascular disease. As a re…

q-bio.QM2023

Quantitative modeling and simulation of biochemical processes in the human body

Jacob Bendsen, Peter Emil Carstensen, Asbjørn Thode Reenberg +2

We present a whole-body model of human metabolism that utilizes a system of organs and blood vessels to simulate the enzymatic reactions. The model focuses on key organs, including…

q-bio.QM2022

A whole-body multi-scale mathematical model for dynamic simulation of the metabolism in man

Peter Emil Carstensen, Jacob Bendsen, Asbjørn Thode Reenberg +2

We propose a whole-body model of the metabolism in man as well as a generalized approach for modeling metabolic networks. Using this approach, we are able to write a large metaboli…