1 citations · 3 across the 5 of their papers we have counts for
5 papers
A whole-body multi-scale mathematical model for dynamic simulation of the metabolism in man
Peter Emil Carstensen, Jacob Bendsen, Asbjørn Thode Reenberg +2
We propose a whole-body model of the metabolism in man as well as a generalized approach for modeling metabolic networks. Using this approach, we are able to write a large metaboli…
Large-scale Virtual Clinical Trials of Closed-loop Treatments for People with Type 1 Diabetes
Tobias K. S. Ritschel, Asbjørn Thode Reenberg, John Bagterp Jørgensen
We propose a virtual clinical trial for assessing the safety and efficacy of closed-loop diabetes treatments prior to an actual clinical trial. Such virtual trials enable rapid and…
Nonlinear Model Predictive Control and System Identification for a Dual-hormone Artificial Pancreas
Asbjørn Thode Reenberg, Tobias K. S. Ritschel, Emilie B. Lindkvist +5
In this work, we present a switching nonlinear model predictive control (NMPC) algorithm for a dual-hormone artificial pancreas (AP), and we use maximum likelihood estimation (MLE)…
High-performance Uncertainty Quantification in Large-scale Virtual Clinical Trials of Closed-loop Diabetes Treatment
Asbjørn Thode Reenberg, Tobias K. S. Ritschel, Bernd Dammann +1
In this paper, we propose a virtual clinical trial for assessing the performance and identifying risks in closed-loop diabetes treatments. Virtual clinical trials enable fast and r…
A one-size-fits-all artificial pancreas for people with type 1 diabetes based on physiological insight and feedback control
Tobias K. S. Ritschel, Asbjørn Thode Reenberg, Emilie B. Lindkvist +6
We propose a model-free artificial pancreas (AP) for people with type 1 diabetes. The algorithmic parameters are tuned to a virtual population of 1,000,000 individuals, and the AP…