1 citations · 3 across the 7 of their papers we have counts for
7 papers
Mathematical meal models for simulation of human metabolism
Tobias K. S. Ritschel, Asbjørn Thode Reenberg, Peter Emil Carstensen +2
We present and critically discuss five commonly used mathematical models of the meal glucose rate of appearance in humans. Such models are key to simulation of the metabolism in he…
Quantitative modeling and simulation of biochemical processes in the human body
Jacob Bendsen, Peter Emil Carstensen, Asbjørn Thode Reenberg +2
We present a whole-body model of human metabolism that utilizes a system of organs and blood vessels to simulate the enzymatic reactions. The model focuses on key organs, including…
A whole-body multi-scale mathematical model for dynamic simulation of the metabolism in man
Peter Emil Carstensen, Jacob Bendsen, Asbjørn Thode Reenberg +2
We propose a whole-body model of the metabolism in man as well as a generalized approach for modeling metabolic networks. Using this approach, we are able to write a large metaboli…
Large-scale Virtual Clinical Trials of Closed-loop Treatments for People with Type 1 Diabetes
Tobias K. S. Ritschel, Asbjørn Thode Reenberg, John Bagterp Jørgensen
We propose a virtual clinical trial for assessing the safety and efficacy of closed-loop diabetes treatments prior to an actual clinical trial. Such virtual trials enable rapid and…
Nonlinear Model Predictive Control and System Identification for a Dual-hormone Artificial Pancreas
Asbjørn Thode Reenberg, Tobias K. S. Ritschel, Emilie B. Lindkvist +5
In this work, we present a switching nonlinear model predictive control (NMPC) algorithm for a dual-hormone artificial pancreas (AP), and we use maximum likelihood estimation (MLE)…
High-performance Uncertainty Quantification in Large-scale Virtual Clinical Trials of Closed-loop Diabetes Treatment
Asbjørn Thode Reenberg, Tobias K. S. Ritschel, Bernd Dammann +1
In this paper, we propose a virtual clinical trial for assessing the performance and identifying risks in closed-loop diabetes treatments. Virtual clinical trials enable fast and r…
A one-size-fits-all artificial pancreas for people with type 1 diabetes based on physiological insight and feedback control
Tobias K. S. Ritschel, Asbjørn Thode Reenberg, Emilie B. Lindkvist +6
We propose a model-free artificial pancreas (AP) for people with type 1 diabetes. The algorithmic parameters are tuned to a virtual population of 1,000,000 individuals, and the AP…