21 citations · 37 across the 5 of their papers we have counts for
5 papers
Pearl: A Foundation Model for Placing Every Atom in the Right Location
Genesis Research Team, Alejandro Dobles, Nina Jovic +37
Accurately predicting the three-dimensional structures of protein-ligand complexes remains a fundamental challenge in computational drug discovery that limits the pace and success…
Neural Design for Genetic Perturbation Experiments
Aldo Pacchiano, Drausin Wulsin, Robert A. Barton +1
The problem of how to genetically modify cells in order to maximize a certain cellular phenotype has taken center stage in drug development over the last few years (with, for examp…
SystemMatch: optimizing preclinical drug models to human clinical outcomes via generative latent-space matching
Scott Gigante, Varsha G. Raghavan, Amanda M. Robinson +7
Translating the relevance of preclinical models (, animal models, or organoids) to their relevance in humans presents an important challenge during drug developm…
Modeling the Complex Dynamics and Changing Correlations of Epileptic Events
Drausin F. Wulsin, Emily B. Fox, Brian Litt
Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of eve…
A Hierarchical Dirichlet Process Model with Multiple Levels of Clustering for Human EEG Seizure Modeling
Drausin Wulsin, Shane Jensen, Brian Litt
Driven by the multi-level structure of human intracranial electroencephalogram (iEEG) recordings of epileptic seizures, we introduce a new variant of a hierarchical Dirichlet Proce…