2 papers
q-bio.GN2024
Perspective on recent developments and challenges in regulatory and systems genomics
Julia Zeiltinger, Sushmita Roy, Ferhat Ay +5
Predicting how genetic variation affects phenotypic outcomes at the organismal, cellular, and molecular levels requires deciphering the cis-regulatory code, the sequence rules by w…
math.DS2022
Stochastic mRNA production by a three-state gene
Boris Rubinstein, Jay Unruh, Julia Zeitlinger
We consider a model of mRNA production governed by the dynamics of a gene that exists in three possible states -- inactive, poised and active. The transitions between the adjacent…