4 papers
Sub-micromolar imaging of intrinsic chromophores by two-photon photothermal microscopy captures mitochondrial response to chemotherapy
Nathaniel Hai, Chinmayee Vallabh Prabhu Dessai, Dingcheng Sun +4
Intracellular chromophores (e.g., NADH and FAD) play a central role in regulation of cellular metabolism. Though autofluorescence has been extensively used for label-free mapping o…
Label-free Imaging of Single-Biomolecule Structure and Interaction by Stimulated Raman Photothermal Encoded Scattering
Pin-Tian Lyu, Yifan Zhu, Qing Xia +8
Current single molecule methods either rely on fluorescence or lack chemical information. Here we report stimulated Raman photothermal encoded scattering (SRPSCAT) microscopy for q…
Label-free optical imaging of ion channel activity on living cells
Qing-Yue Li, Pin-Tian Lyu, Bin Kang +2
Deciphering ion channel activity and signaling interactions within cells is one of the key tasks of neuroscience. Currently, measuring this electrophysiological activity is done us…
Decrypting material performance by wide-field femtosecond interferometric imaging of energy carrier evolution
Pin-Tian Lyu, Qing-Yue Li, Pei Wu +4
Energy carrier evolution is crucial for material performance. Ultrafast microscopy has been widely applied to visualize the spatiotemporal evolution of energy carriers. However, di…