5 papers
Fluidization in Growth-Induced Morphogenesis
Min Wu
Elastic buckling has explained shape formation in growing tissues, yet the role of tissue fluidity remains elusive. We derive a minimal fluidized growth-elasticity model as a nonli…
Continuum modeling of fluidic and elastic flow during growth-driven wound closure in partial-EMT cell monolayers
Chaozhen Wei, Han Jiang, Yifan Gu +5
Large-scale circular gap closure occurs over a time scale on which cell growth and proliferation become important. Growth is the main driver of the closing process, while cell dyna…
Chemomechanical regulation of growing tissues from a thermodynamically-consistent framework and its application to tumor spheroid growth
Nonthakorn Olaranont, Chaozhen Wei, John Lowengrub +1
It is widely recognized that reciprocal interactions between cells and their microenvironment, via mechanical forces and biochemical signaling pathways, regulate cell behaviors dur…
Inferring relative surface elastic moduli in thin-wall models of single cells
Yaqi Deng, Chaozhen Wei, Rholee Xu +2
There is a growing interest in measuring the cell wall mechanical property at different locations in single walled cells. We present an inference scheme that maps relative surface…
An Eulerian nonlinear elastic model for compressible and fluidic tissue with radially symmetric growth
Chaozhen Wei, Min Wu
Cell proliferation, apoptosis, and myosin-dependent contraction can generate elastic stress and strain in living tissues, which may be dissipated by internal rearrangement through…