2 papers
q-bio.BM2009★ 121 cited
Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric aggregates
Stefan Auer, Filip Meersman, Christopher M. Dobson +1
The presence of oligomeric aggregates, which is often observed during the process of amyloid formation, has recently attracted much attention since it has been associated with neur…
q-bio.BM2009★ 103 cited
Self-Templated Nucleation in Peptide and Protein aggregation
Stefan Auer, Christopher M. Dobson, Michele Vendruscolo +1
Peptides and proteins exhibit a common tendency to assemble into highly ordered fibrillar aggregates, whose formation proceeds in a nucleation-dependent manner that is often preced…