4 papers
Comparative analysis of resistive immersed surface and immersed boundary methods for aortic valve simulation
Han Zhao, Alexander D. Kaiser, Fanwei Kong +5
Numerical modeling of aortic valve dynamics is essential for understanding the complex fluid-structure interaction (FSI) governing valve biomechanics in health and disease. Immerse…
Semi-Automated Generation and Hemodynamic Assessment of Surgical Baffle Geometry for Biventricular Repair
Elena Sabdy Martinez, Alexander D. Kaiser, Alexander K. Reed +6
Patient-specific computational modeling has emerged as a powerful tool for surgical planning in complex congenital heart disease. One promising application is complex biventricular…
Simulations Predict Improved Valve Performance Without Direct Leaflet Intervention After Neonatal Truncus Arteriosus Repair
Karoline-Marie Bornemann, Perry S. Choi, Jay Huber +6
Truncus arteriosus (TA) is a rare and severe congenital heart disease. Quadricuspid valve morphology occurs in 25% of all TA patients and is linked to regurgitation and increased r…
A Fluid-Structure Interaction Model of the Zebrafish Aortic Valve
Alexander D. Kaiser, Jing Wang, Aaron L. Brown +3
The zebrafish is a valuable model organism for studying cardiac development and diseases due to its many shared aspects of genetics and anatomy with humans and ease of experimental…