19 citations · 19 across the 2 of their papers we have counts for
2 papers
stat.AP2020
Shrinkage estimation for dose-response modeling in phase II trials with multiple schedules
Burak Kürsad Günhan, Paul Meyvisch, Tim Friede
Recently, phase II trials with multiple schedules (frequency of administrations) have become more popular, for instance in the development of treatments for atopic dermatitis. If t…
stat.ME2020★ 19 cited
A Bayesian time-to-event pharmacokinetic model for phase I dose-escalation trials with multiple schedules
Burak Kürsad Günhan, Sebastian Weber, Tim Friede
Phase I dose-escalation trials must be guided by a safety model in order to avoid exposing patients to unacceptably high risk of toxicities. Traditionally, these trials are based o…