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physics.med-ph2025

Steerable Conditional Diffusion for Domain Adaptation in PET Image Reconstruction

George Webber, Alexander Hammers, Andrew P. King +1

Diffusion models have recently enabled state-of-the-art reconstruction of positron emission tomography (PET) images while requiring only image training data. However, domain shift…

physics.med-ph2025

Personalized MR-Informed Diffusion Models for 3D PET Image Reconstruction

George Webber, Alexander Hammers, Andrew P. King +1

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by lev…

physics.med-ph2025

Supervised Diffusion-Model-Based PET Image Reconstruction

George Webber, Alexander Hammers, Andrew P King +1

Diffusion models (DMs) have recently been introduced as a regularizing prior for PET image reconstruction, integrating DMs trained on high-quality PET images with unsupervised sche…

physics.med-ph2025

Likelihood-Scheduled Score-Based Generative Modeling for Fully 3D PET Image Reconstruction

George Webber, Yuya Mizuno, Oliver D. Howes +3

Medical image reconstruction with pre-trained score-based generative models (SGMs) has advantages over other existing state-of-the-art deep-learned reconstruction methods, includin…

physics.med-ph2024

Multi-Subject Image Synthesis as a Generative Prior for Single-Subject PET Image Reconstruction

George Webber, Yuya Mizuno, Oliver D. Howes +3

Large high-quality medical image datasets are difficult to acquire but necessary for many deep learning applications. For positron emission tomography (PET), reconstructed image qu…

physics.med-ph2024

Generative-Model-Based Fully 3D PET Image Reconstruction by Conditional Diffusion Sampling

George Webber, Yuya Mizuno, Oliver D. Howes +3

Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have d…