activity
20172026
most citedParameter Estimation for Mixed-Mechanism Tear Film Thinning

10 citations · 19 across the 10 of their papers we have counts for

collaborators

14 papers

math.NA2026

Amortized Generative Modeling of Invariant Measures across A Family of Kuramoto-Sivashinsky PDEs

Arnab Roy, Tobin A. Driscoll

The long-run statistics of chaotic dissipative partial differential equations are described by invariant measures, and when the equation carries a parameter these measures form a f…

math.NA2026

Parameter estimation for evaporation-driven tear film model in two space dimensions

Qinying Chen, Tobin Driscoll

The tear film (TF) plays a critical role in maintaining ocular surface health, and its disruption through tear breakup (TBU) is closely associated with dry eye disease. Evaporation…

math.NA2026

Stable evaluation of derivatives for barycentric and continued fraction representations of rational functions

Tobin A. Driscoll, Yuxing Zhou

Fast algorithms for approximation by rational functions exist for both barycentric and Thiele continued fraction (TCF) representations. We present the first numerically stable meth…

math.NA2026

Operator learning for models of tear film breakup

Qinying Chen, Arnab Roy, Tobin A. Driscoll

Tear film (TF) breakup is a key driver of understanding dry eye disease, yet estimating TF thickness and osmolarity from fluorescence (FL) imaging typically requires solving comput…

math.NA2025

RationalFunctionApproximation.jl: Rational Approximation On Discrete and Continuous Domains

Tobin A. Driscoll

Unlike polynomials, rational functions can represent functions having poles or branch cuts with root-exponential convergence and no Runge phenomenon. Recent developments of the AAA…

math.NA2025★ 1 cited

Greedy Thiele continued-fraction approximation on continuum domains in the complex plane

Tobin A. Driscoll, Yuxing Zhou

We describe an adaptive greedy algorithm for Thiele continued-fraction (TCF) approximation of a function defined on a continuum domain in the complex plane. The algorithm iterative…

math.NA2024★ 4 cited

Evaporation-driven tear film thinning and breakup in two space dimensions

Qinying Chen, Tobin A. Driscoll, Richard J. Braun

Evaporation profiles have a strong effect on tear film thinning and breakup (TBU), a key factor in dry eye disease (DED). In experiments, TBU is typically seen to occur in patterns…

physics.flu-dyn2023★ 4 cited

Extensional Flow of a Free Film of Nematic Liquid Crystal with Moderate Elasticity

M. J. Taranchuk, L. J. Cummings, T. A. Driscoll +1

Motivated by problems arising in tear film dynamics, we present a model for the extensional flow of thin sheets of nematic liquid crystal. The rod-like molecules of these substance…

math.NA2022

Fitting ODE models of tear film breakup

Tobin A. Driscoll, Richard J. Braun, Rayanne A. Luke +5

The contribution of different physical effects to tear breakup (TBU) in subjects with no self-reported history of dry eye are quantified. An automated system using a convolutional…

physics.flu-dyn2020★ 10 cited

Parameter Estimation for Mixed-Mechanism Tear Film Thinning

Rayanne A. Luke, Richard J. Braun, Tobin A. Driscoll +2

Etiologies of tear breakup include evaporation-driven, divergent flow-driven, and a combination of these two. A mathematical model incorporating evaporation and lipid-driven tangen…

math.NA2019

Preconditioned nonlinear iterations for overlapping Chebyshev discretizations with independent grids

Kevin W. Aiton, Tobin A. Driscoll

The additive Schwarz method is usually presented as a preconditioner for a PDE linearization based on overlapping subsets of nodes from a global discretization. It has previously b…

math.NA2018

An adaptive partition of unity method for multivariate Chebyshev polynomial approximations

Kevin W. Aiton, Tobin A. Driscoll

Spectral polynomial approximation of smooth functions allows real-time manipulation of and computation with them, as in the Chebfun system. Extension of the technique to two-dimens…

math.NA2017

An adaptive partition of unity method for Chebyshev polynomial interpolation

Kevin W. Aiton, Tobin A. Driscoll

For a function that is analytic on and around an interval, Chebyshev polynomial interpolation provides spectral convergence. However, if the function has a singularity close to the…

math.NA2017

Simulation of Parabolic Flow on an Eye-Shaped Domain with Moving Boundary

Tobin A. Driscoll, Richard J. Braun, Joseph K. Brosch

During the upstroke of a normal eye blink, the upper lid moves and paints a thin tear film over the exposed corneal and conjunctival surfaces. This thin tear film may be modeled by…