455 citations · 988 across the 4 of their papers we have counts for
4 papers
Community recommendations on cryoEM data archiving and validation
Gerard J. Kleywegt, Paul D. Adams, Sarah J. Butcher +44
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle anal…
Deep learning based mixed-dimensional GMM for characterizing variability in CryoEM
Muyuan Chen, Steven Ludtke
Structural flexibility and/or dynamic interactions with other molecules is a critical aspect of protein function. CryoEM provides direct visualization of individual macromolecules…
A complete data processing workflow for CryoET and subtomogram averaging
Muyuan Chen, James M. Bell, Xiaodong Shi +3
Electron cryotomography (CryoET) is currently the only method capable of visualizing cells in 3D at nanometer resolutions. While modern instruments produce massive amounts of tomog…
Convolutional Neural Networks for Automated Annotation of Cellular Cryo-Electron Tomograms
Muyuan Chen, Wei Dai, Ying Sun +5
Cellular Electron Cryotomography (CryoET) offers the ability to look inside cells and observe macromolecules frozen in action. A primary challenge for this technique is identifying…