25 citations · 34 across the 4 of their papers we have counts for
4 papers
Phase separation and protein partitioning in compartmentalized cell-free expression reactions
Shuzo Kato, David Garenne, Vincent Noireaux +1
Liquid-liquid phase separation (LLPS) is important to control a wide range of reactions from gene expression to protein degradation in a cell-sized space. To bring a better underst…
Proofreading mechanism of Class 2 CRISPR-Cas systems
Aset Khakimzhan, David Garenne, Benjamin I. Tickman +3
CRISPR systems experience off-target effects that interfere with the ability to accurately perform genetic edits. While empirical models predict off-target effects in specific plat…
Growth and instability of a phospholipid vesicle in a bath of fatty acids
Julien Dervaux, Vincent Noireaux, Albert Libchaber
Using a microfluidic trap, we study the behavior of individual phospholipid vesicles in contact with fatty acids. We show that spontaneous fatty acids insertion inside the bilayer…
Biomolecular resource utilization in elementary cell-free gene circuits
Dan Siegal-Gaskins, Vincent Noireaux, Richard M. Murray
We present a detailed dynamical model of the behavior of transcription-translation circuits in vitro that makes explicit the roles played by essential molecular resources. A set of…