5 citations · 5 across the 3 of their papers we have counts for
3 papers
stat.ME2022
Stratified modestly-weighted log-rank tests in settings with an anticipated delayed separation of survival curves
Dominic Magirr, José L. Jiménez
Delayed separation of survival curves is a common occurrence in confirmatory studies in immuno-oncology. Many novel statistical methods that aim to efficiently capture potential lo…
stat.ME2021★ 5 cited
Combining cytotoxic agents with continuous dose levels in seamless phase I-II clinical trials
José L. Jiménez, Mourad Tighiouart
Phase I-II cancer clinical trial designs are intended to accelerate drug development. In cases where efficacy cannot be ascertained in a short period of time, it is common to divid…
stat.AP2021
Design and Analysis of group-sequential clinical trials based on a modestly-weighted log-rank test in anticipation of a delayed separation of survival curves: A practical guidance
Dominic Magirr, José L. Jiménez
A common feature of many recent trials evaluating the effects of immunotherapy on survival is that non-proportional hazards can be anticipated at the design stage. This raises the…