activity
20212025
most citedIn Situ Melting and Revitrification as an Approach to Microsecond Time-Resolved Cryo-Electron Microscopy

68 citations · 97 across the 7 of their papers we have counts for

collaborators

7 papers

physics.ins-det2025

An Instrument for Physical Vapor Deposition onto Cryo-EM Samples for Microsecond Time-Resolved Cryo-EM

Wyatt A. Curtis, Constantin R. Krüger, Axel P. Tracol Gavard +3

Laser flash melting and revitrification experiments have recently improved the time resolution of cryo-electron microscopy (cryo-EM) to the microsecond timescale, making it fast en…

physics.chem-ph2024★ 3 cited

Direct Measurement of the Critical Cooling Rate for the Vitrification of Water

Nathan J. Mowry, Constantin R. Kruger, Marcel Drabbels +1

The vitrification of aqueous solutions through rapid cooling is a remarkable achievement that launched the field of cryo-electron microscopy (cryo-EM) and has enabled the cryoprese…

physics.bio-ph2024★ 1 cited

Microsecond Time-Resolved Cryo-Electron Microscopy

Ulrich J. Lorenz

Microsecond time-resolved cryo-electron microscopy has emerged as a novel approach for directly observing proteins dynamics. By providing microsecond temporal and near-atomic spati…

physics.chem-ph2024★ 1 cited

Shaped Laser Pulses for Microsecond Time-Resolved Cryo-EM: Outrunning Crystallization During Flash Melting

Constantin R. Krüger, Nathan J. Mowry, Marcel Drabbels +1

Water vitrifies if cooled at rates above K/s. Surprisingly, this process cannot simply be reversed by heating the resulting amorphous ice at a similar rate. Instead,…

physics.chem-ph2023

Flash Melting Amorphous Ice

Nathan J. Mowry, Constantin R. Krüger, Gabriele Bongiovanni +2

Water can be vitrified if it is cooled at rates exceeding K/s. This makes it possible to outrun crystallization in so-called no man's land, a range of deeply supercooled t…

physics.chem-ph2022★ 24 cited

Electron Diffraction of Water in No Man's Land

Constantin R. Krüger, Nathan J. Mowry, Gabriele Bongiovanni +2

A generally accepted understanding of the anomalous properties of water will only emerge if it becomes possible to systematically characterize water in the deeply supercooled regim…

physics.bio-ph2021★ 68 cited

In Situ Melting and Revitrification as an Approach to Microsecond Time-Resolved Cryo-Electron Microscopy

Jonathan M. Voss, Oliver F. Harder, Pavel K. Olshin +2

Proteins typically undergo conformational dynamics on the microsecond to millisecond timescale as they perform their function, which is much faster than the time-resolution of cryo…