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physics.chem-ph2026

Streamlining Analysis and Design of Two-Dimensional Electronic Spectroscopy using Machine Learning

Nicholas I. Hausman, Joseph Kelly, Michael S. Chen +6

Two-dimensional electronic spectroscopy (2DES) offers unique insights into the coupling between electronic and nuclear motion and dynamics, making it a key technique in diverse fie…

physics.chem-ph2025

Two-dimensional electronic spectroscopy in the condensed phase using equivariant transformer accelerated molecular dynamics simulations

Joseph Kelly, Frank Hu, Arianna Damiani +10

Two-dimensional electronic spectroscopy (2DES) provides rich information about how the electronic states of molecules, proteins, and solid-state materials interact with each other…

physics.chem-ph2024

On the design space between molecular mechanics and machine learning force fields

Yuanqing Wang, Kenichiro Takaba, Michael S. Chen +14

A force field as accurate as quantum mechanics (QM) and as fast as molecular mechanics (MM), with which one can simulate a biomolecular system efficiently enough and meaningfully e…

physics.chem-ph2024

Accurate and efficient structure elucidation from routine one-dimensional NMR spectra using multitask machine learning

Frank Hu, Michael S. Chen, Grant M. Rotskoff +2

Rapid determination of molecular structures can greatly accelerate workflows across many chemical disciplines. However, elucidating structure using only one-dimensional (1D) NMR sp…

physics.chem-ph2024

Quantum Hardware-Enabled Molecular Dynamics via Transfer Learning

Abid Khan, Prateek Vaish, Yaoqi Pang +8

The ability to perform ab initio molecular dynamics simulations using potential energies calculated on quantum computers would allow virtually exact dynamics for chemical and bioch…