4 papers · 1 filter
A behavior-environment information loop drives sensory navigation
Kevin S. Chen, Matthew P. Leighton, Damon A. Clark +1
As organisms navigate the environment to locate critical resources, their behavioral actions must be tightly coupled to their sensory inputs. Here, we introduce an information-theo…
Chiral phase-coexistence in compressed double-twist elastomers
Matthew P. Leighton, Laurent Kreplak, Andrew D. Rutenberg
We adapt the theory of anisotropic rubber elasticity to model cross-linked double-twist liquid crystal cylinders such as exhibited in biological systems. In mechanical extension we…
D-band strain underestimates fibril strain for twisted collagen fibrils at low strains
Matthew P. Leighton, Andrew D. Rutenberg, Laurent Kreplak
Collagen fibrils are the main structural component of load-bearing tissues such as tendons, ligaments, skin, the cornea of the eye, and the heart. The D-band of collagen fibrils is…
Non-equilibrium Growth and Twist of Cross-Linked Collagen Fibrils
Matthew P. Leighton, Laurent Kreplak, Andrew D. Rutenberg
The lysyl oxidase (LOX) enzyme that catalyses cross-link formation during the assembly of collagen fibrils in vivo is too large to diffuse within assembled fibrils, and so is incom…