activity
20202026
most citedA computational framework for modeling cell-matrix interactions in soft biological tissues

52 citations · 125 across the 11 of their papers we have counts for

collaborators

15 papers

cond-mat.mtrl-sci2026

Inelastic Constitutive Kolmogorov-Arnold Networks: A generalized framework for automated discovery of interpretable inelastic material models

Chenyi Ji, Kian P. Abdolazizi, Hagen Holthusen +2

A key problem of solid mechanics is the identification of the constitutive law of a material, that is, the relation between strain history and stress. Machine learning has lead to…

physics.comp-ph2025

Machine-learned domain partitioning for computationally efficient coupling of continuum and particle simulations of membrane fabrication

Matthias Busch, Gregor Häfner, Jiayu Xie +4

All simulation approaches eventually face limits in computational scalability when applied to large spatiotemporal domains. This challenge becomes especially apparent in molecular-…

cs.CE2025★ 1 cited

Electromechanical computational model of the human stomach

Maire S. Henke, Sebastian Brandstaeter, Sebastian L. Fuchs +3

The stomach plays a central role in digestion through coordinated muscle contractions, known as gastric peristalsis, driven by slow-wave electrophysiology. Understanding this proce…

q-bio.TO2025

A 3D-1D-0D Multiscale Model of the Neuro-Glial-Vascular Unit for Synaptic and Vascular Dynamics in the Dorsal Vagal Complex

Alexander Hermann, Tobias Köppl, Andreas Wagner +5

Cerebral blood flow regulation is critical for brain function, and its disruption is implicated in various neurological disorders. Many existing models do not fully capture the com…

physics.comp-ph2025

Constitutive Kolmogorov-Arnold Networks (CKANs): Combining Accuracy and Interpretability in Data-Driven Material Modeling

Kian P. Abdolazizi, Roland C. Aydin, Christian J. Cyron +1

Hybrid constitutive modeling integrates two complementary approaches for describing and predicting a material's mechanical behavior: purely data-driven black-box methods and physic…

q-bio.TO2024

A Calibration Approach for Elasticity Estimation with Medical Tools

Sarah Grube, Maximilian Neidhardt, Anna-Katarina Herrmann +5

Soft tissue elasticity is directly related to different stages of diseases and can be used for tissue identification during minimally invasive procedures. By palpating a tissue wit…

cs.LG2024

ECToNAS: Evolutionary Cross-Topology Neural Architecture Search

Elisabeth J. Schiessler, Roland C. Aydin, Christian J. Cyron

We present ECToNAS, a cost-efficient evolutionary cross-topology neural architecture search algorithm that does not require any pre-trained meta controllers. Our framework is able…

cond-mat.mtrl-sci2023

Viscoelastic Constitutive Artificial Neural Networks (vCANNs) a framework for data-driven anisotropic nonlinear finite viscoelasticity

Kian P. Abdolazizi, Kevin Linka, Christian J. Cyron

The constitutive behavior of polymeric materials is often modeled by finite linear viscoelastic (FLV) or quasi-linear viscoelastic (QLV) models. These popular models are simplifica…

eess.IV2022

Ultrasound Shear Wave Elasticity Imaging with Spatio-Temporal Deep Learning

Maximilian Neidhardt, Marcel Bengs, Sarah Latus +4

Ultrasound shear wave elasticity imaging is a valuable tool for quantifying the elastic properties of tissue. Typically, the shear wave velocity is derived and mapped to an elastic…

q-bio.TO2022

A homogenized constrained mixture model of cardiac growth and remodeling: Analyzing mechanobiological stability and reversal

Amadeus M. Gebauer, Martin R. Pfaller, Fabian A. Braeu +2

Cardiac growth and remodeling (G&R) patterns change ventricular size, shape, and function both globally and locally. Biomechanical, neurohormonal, and genetic stimuli drive these p…

cs.CE2022

A Versatile SPH Modeling Framework for Coupled Microfluid-Powder Dynamics in Additive Manufacturing: Binder Jetting, Material Jetting, Directed Energy Deposition and Powder Bed Fusion

Sebastian L. Fuchs, Patrick M. Praegla, Christian J. Cyron +2

Many additive manufacturing (AM) technologies rely on powder feedstock, which is fused to form the final part either by melting or by chemical binding with subsequent sintering. In…

q-bio.CB2021★ 12 cited

What do cells regulate in soft tissues on short time scales?

Jonas F. Eichinger, Daniel Paukner, Roland C. Aydin +3

Cells within living soft biological tissues seem to promote the maintenance of a mechanical state within a defined range near a so-called set-point. This mechanobiological process…

cs.CE2021★ 52 cited

A computational framework for modeling cell-matrix interactions in soft biological tissues

Jonas F. Eichinger, Maximilian J. Grill, Iman Davoodi Kermani +4

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is of…

cs.CE2021★ 19 cited

An SPH framework for fluid-solid and contact interaction problems including thermo-mechanical coupling and reversible phase transitions

Sebastian L. Fuchs, Christoph Meier, Wolfgang A. Wall +1

The present work proposes an approach for fluid-solid and contact interaction problems including thermo-mechanical coupling and reversible phase transitions. The solid field is ass…

cs.CE2020★ 41 cited

A novel smoothed particle hydrodynamics and finite element coupling scheme for fluid-structure interaction: the sliding boundary particle approach

Sebastian L. Fuchs, Christoph Meier, Wolfgang A. Wall +1

A novel numerical formulation for solving fluid-structure interaction (FSI) problems is proposed where the fluid field is spatially discretized using smoothed particle hydrodynamic…