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physics.med-ph2025
Mapping intratumoral heterogeneity through PET-derived washout and deep learning after proton therapy
Pablo Cabrales, David Izquierdo-García, Víctor V. Onecha +4
The distribution of produced isotopes during proton therapy can be imaged with Positron Emission Tomography (PET) to verify dose delivery. However, biological washout, driven by ti…
physics.med-ph2024
Activation measurements of an iodinated contrast media for online range verification in proton therapy
A. Espinosa-Rodriguez, V. V. Onecha, V. M. Nouvilas +6
The use of contrast agents has previously been proposed as a novel method to increase the activation close to the Bragg peak, aiming to improve the quality of proton range monitori…
physics.med-ph2021
Could 18O-enriched water increase signal for PET proton range verification? A study using a chicken embryo model
Samuel España, Daniel Sánchez-Parcerisa, Paloma Bragado +9
Range verification of clinical protontherapy systems via positron-emission tomography (PET) still suffers from insufficient signal from low-energy protons around the Bragg peak and…