9 citations · 10 across the 4 of their papers we have counts for
5 papers
A billion years of evolution manifest in nanosecond protein dynamics
Philipp J. Heckmeier, Jeannette Ruf, Charlotte Rochereau +1
Protein dynamics form a critical bridge between protein structure and function, yet the impact of evolution on ultrafast processes inside proteins remains enigmatic. This study del…
Transient 2D IR spectroscopy and multiscale simulations reveal vibrational couplings in the Cyanobacteriochrome Slr1393-g3
David Buhrke, Yigal Lahav, Aditya Rao +3
Cyanobacteriochromes are bi-stable photoreceptor proteins with desirable photochemical properties for biotechnological applications such as optogenetics or fluorescence microscopy.…
MCL-1 promiscuity and the structural resilience of its binding partners
Philipp J. Heckmeier, Jeannette Ruf, Brankica G. Janković +1
MCL-1 and its natural inhibitors, the BH3-only proteins PUMA, BIM, and NOXA regulate apoptosis by interacting promiscuously within an entangled binding network. Little is known abo…
The Speed of Allosteric Signaling Within a Single-Domain Protein
Olga Bozovic, Jeannette Ruf, Claudio Zanobini +4
While much is known about different allosteric regulation mechanisms, the nature of the "allosteric signal", and the timescale on which it propagates, remains elusive. The PDZ3 dom…
Sequence of Events During Peptide Unbinding from RNase S: A Complete Experimental Description
Brankica Jankovic, Jeannette Ruf, Claudio Zanobini +3
The photo-triggered unbinding of the intrinsically disordered S-peptide from the RNase S complex is studied with the help of transient IR spectroscopy, covering a wide range of tim…