1 citations · 1 across the 5 of their papers we have counts for
5 papers
Prior Effective Sample Size When Borrowing on the Treatment Effect Scale
Hongtao Zhang, Keaven M Anderson, Zachary Zimmer +3
With the robust uptick in the applications of Bayesian external data borrowing, eliciting a prior distribution with the proper amount of information becomes increasingly critical.…
Weighting Based Approaches to Borrowing Historical Controls for Indirect comparison for Time-to-Event Data with a Cure Fraction
Jixian Wang, Hongtao Zhang, Ram Tiwari
To use historical controls for indirect comparison with single-arm trials, the population difference between data sources should be adjusted to reduce confounding bias. The adjustm…
A Propensity-Score Integrated Approach to Bayesian Dynamic Power Prior Borrowing
Jixian Wang, Hongtao Zhang, Ram Tiwari
Use of historical control data to augment a small internal control arm in a randomized control trial (RCT) can lead to significant improvement of the efficiency of the trial. It in…
An Empirical Bayes Robust Meta-Analytical-Predictive Prior to Adaptively Leverage External Data
Hongtao Zhang, Yueqi Shen, Alan Y Chiang +1
We propose a novel empirical Bayes robust MAP (EB-rMAP) prior to adaptively leverage external/historical data. Built on Box's prior predictive p-value, the EB-rMAP prior framework…
Improving the Performance of Bayesian Logistic Regression Model with Overdose Control in Oncology Dose-Finding Studies
Hongtao Zhang, Alan Y Chiang, Jixian Wang
An accurately identified maximum tolerated dose (MTD) serves as the cornerstone of successful subsequent phases in oncology drug development. Bayesian logistic regression model (BL…