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q-bio.BM2025
Fast and Accurate Antibody Sequence Design via Structure Retrieval
Xingyi Zhang, Kun Xie, Ningqiao Huang +5
Recent advancements in protein design have leveraged diffusion models to generate structural scaffolds, followed by a process known as protein inverse folding, which involves seque…
q-bio.BM2025
Towards More Accurate Full-Atom Antibody Co-Design
Jiayang Wu, Xingyi Zhang, Xiangyu Dong +5
Antibody co-design represents a critical frontier in drug development, where accurate prediction of both 1D sequence and 3D structure of complementarity-determining regions (CDRs)…