97 citations · 109 across the 24 of their papers we have counts for
25 papers
DeepFixel: Crossing white matter fiber identification through spherical convolutional neural networks
Adam M. Saunders, Lucas W. Remedios, Elyssa M. McMaster +6
Diffusion-weighted magnetic resonance imaging allows for reconstruction of models for structural connectivity in the brain, such as fiber orientation distribution functions (ODFs)…
Phenotype discovery of traumatic brain injury segmentations from heterogeneous multi-site data
Adam M. Saunders, Michael E. Kim, Gaurav Rudravaram +8
Traumatic brain injury (TBI) is intrinsically heterogeneous, and typical clinical outcome measures like the Glasgow Coma Scale complicate this diversity. The large variability in s…
Lifespan Pancreas Morphology for Control vs Type 2 Diabetes using AI on Largescale Clinical Imaging
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz +11
Purpose: Understanding how the pancreas changes is critical for detecting deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morph…
Data-Driven Abdominal Phenotypes of Type 2 Diabetes in Lean, Overweight, and Obese Cohorts
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz +10
Purpose: Although elevated BMI is a well-known risk factor for type 2 diabetes, the disease's presence in some lean adults and absence in others with obesity suggests that detailed…
Multipath cycleGAN for harmonization of paired and unpaired low-dose lung computed tomography reconstruction kernels
Aravind R. Krishnan, Thomas Z. Li, Lucas W. Remedios +12
Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such…
Investigating the impact of kernel harmonization and deformable registration on inspiratory and expiratory chest CT images for people with COPD
Aravind R. Krishnan, Yihao Liu, Kaiwen Xu +9
Paired inspiratory-expiratory CT scans enable the quantification of gas trapping due to small airway disease and emphysema by analyzing lung tissue motion in COPD patients. Deforma…
Sensitivity of quantitative diffusion MRI tractography and microstructure to anisotropic spatial sampling
Elyssa M. McMaster, Nancy R. Newlin, Chloe Cho +10
Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster,…
Influence of Early through Late Fusion on Pancreas Segmentation from Imperfectly Registered Multimodal MRI
Lucas W. Remedios, Han Liu, Samuel W. Remedios +7
Multimodal fusion promises better pancreas segmentation. However, where to perform fusion in models is still an open question. It is unclear if there is a best location to fuse inf…
Comparison and calibration of MP2RAGE quantitative T1 values to multi-TI inversion recovery T1 values
Adam M. Saunders, Michael E. Kim, Chenyu Gao +6
While typical qualitative T1-weighted magnetic resonance images reflect scanner and protocol differences, quantitative T1 mapping aims to measure T1 independent of these effects. C…
Harmonized connectome resampling for variance in voxel sizes
Elyssa M. McMaster, Nancy R. Newlin, Gaurav Rudravaram +10
To date, there has been no comprehensive study characterizing the effect of diffusion-weighted magnetic resonance imaging voxel resolution on the resulting connectome for high reso…
Enhancing Single-Slice Segmentation with 3D-to-2D Unpaired Scan Distillation
Xin Yu, Qi Yang, Han Liu +10
2D single-slice abdominal computed tomography (CT) enables the assessment of body habitus and organ health with low radiation exposure. However, single-slice data necessitates the…
Data-driven Nucleus Subclassification on Colon H&E using Style-transferred Digital Pathology
Lucas W. Remedios, Shunxing Bao, Samuel W. Remedios +16
Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell s…
Nucleus subtype classification using inter-modality learning
Lucas W. Remedios, Shunxing Bao, Samuel W. Remedios +14
Understanding the way cells communicate, co-locate, and interrelate is essential to understanding human physiology. Hematoxylin and eosin (H&E) staining is ubiquitously available b…
Evaluation of Mean Shift, ComBat, and CycleGAN for Harmonizing Brain Connectivity Matrices Across Sites
Hanliang Xu, Nancy R. Newlin, Michael E. Kim +15
Connectivity matrices derived from diffusion MRI (dMRI) provide an interpretable and generalizable way of understanding the human brain connectome. However, dMRI suffers from inter…
Super-resolution multi-contrast unbiased eye atlases with deep probabilistic refinement
Ho Hin Lee, Adam M. Saunders, Michael E. Kim +15
Purpose: Eye morphology varies significantly across the population, especially for the orbit and optic nerve. These variations limit the feasibility and robustness of generalizing…
Inter-vendor harmonization of Computed Tomography (CT) reconstruction kernels using unpaired image translation
Aravind R. Krishnan, Kaiwen Xu, Thomas Li +9
The reconstruction kernel in computed tomography (CT) generation determines the texture of the image. Consistency in reconstruction kernels is important as the underlying CT textur…
All-in-SAM: from Weak Annotation to Pixel-wise Nuclei Segmentation with Prompt-based Finetuning
Can Cui, Ruining Deng, Quan Liu +5
The Segment Anything Model (SAM) is a recently proposed prompt-based segmentation model in a generic zero-shot segmentation approach. With the zero-shot segmentation capacity, SAM…
Cell Spatial Analysis in Crohn's Disease: Unveiling Local Cell Arrangement Pattern with Graph-based Signatures
Shunxing Bao, Sichen Zhu, Vasantha L Kolachala +16
Crohn's disease (CD) is a chronic and relapsing inflammatory condition that affects segments of the gastrointestinal tract. CD activity is determined by histological findings, part…
Feasibility of Universal Anomaly Detection without Knowing the Abnormality in Medical Images
Can Cui, Yaohong Wang, Shunxing Bao +11
Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during train…
Democratizing Pathological Image Segmentation with Lay Annotators via Molecular-empowered Learning
Ruining Deng, Yanwei Li, Peize Li +11
Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires lab…
Exploring shared memory architectures for end-to-end gigapixel deep learning
Lucas W. Remedios, Leon Y. Cai, Samuel W. Remedios +8
Deep learning has made great strides in medical imaging, enabled by hardware advances in GPUs. One major constraint for the development of new models has been the saturation of GPU…
Segment Anything Model (SAM) for Digital Pathology: Assess Zero-shot Segmentation on Whole Slide Imaging
Ruining Deng, Can Cui, Quan Liu +13
The segment anything model (SAM) was released as a foundation model for image segmentation. The promptable segmentation model was trained by over 1 billion masks on 11M licensed an…
Cross-scale Multi-instance Learning for Pathological Image Diagnosis
Ruining Deng, Can Cui, Lucas W. Remedios +12
Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (M…
Cross-scale Attention Guided Multi-instance Learning for Crohn's Disease Diagnosis with Pathological Images
Ruining Deng, Can Cui, Lucas W. Remedios +12
Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotation…