3 papers
stat.ME2021
Multi-sample estimation of centered log-ratio matrix in microbiome studies
Yezheng Li, Hongzhe Li, Yuanpei Cao
In microbiome studies, one of the ways of studying bacterial abundances is to estimate bacterial composition based on the sequencing read counts. Various transformations are then a…
stat.ME2017
Multi-sample Estimation of Bacterial Composition Matrix in Metagenomics Data
Yuanpei Cao, Anru Zhang, Hongzhe Li
Metagenomics sequencing is routinely applied to quantify bacterial abundances in microbiome studies, where the bacterial composition is estimated based on the sequencing read count…
stat.ME2016
Large Covariance Estimation for Compositional Data via Composition-Adjusted Thresholding
Yuanpei Cao, Wei Lin, Hongzhe Li
High-dimensional compositional data arise naturally in many applications such as metagenomic data analysis. The observed data lie in a high-dimensional simplex, and conventional st…